Fulcrum Therapeutics, Inc. june 5, 2026 Please complete the form below to contact Kaplan Fox regarding the Fulcrum Therapeutics Investigation: Join a Case First Name * Last Name * Email Address * Phone Number * Ticker Symbol Or Company Name * Please Insert Your Estimation Of Losses In USD * Are you a current or former employee of the company mentioned having traded above? * Yes No Captcha Submit If you are human, leave this field blank. Principal Contacts Jeffrey P. Campisi JCampisi@kaplanfox.comLaurence D. KingLKing@kaplanfox.com Kaplan Fox Encourages Investors of Fulcrum Therapeutics, Inc. (NASDAQ: FULC) to Contact Kaplan Fox Regarding an Investigation into Possible Securities Law Violations Kaplan Fox & Kilsheimer LLP is investigating potential securities violations against Fulcrum Therapeutics, Inc. (“Fulcrum Therapeutics” or the “Company”) (NASDAQ: FULC). CLICK HERE TO RECEIVE MORE INFORMATION ABOUT THIS INVESTIGATION If you are a Fulcrum Therapeutics investor and have suffered losses, or if you have information that could assist in the Fulcrum Therapeutics investigation, you may CLICK HERE to contact us. You may also contact Kaplan Fox by emailing jcampisi@kaplanfox.com or by calling (212) 329-8571. Fulcrum Therapeutics is a “clinical-stage biopharmaceutical company focused on developing small molecules to improve the lives of patients with rare hematological disorders[.]” On June 1, 2026, after market close, Fulcrum Therapeutics announced in a press release “the discontinuation of its pociredir program for the treatment of SCD [(sickle cell disease).]” The Company stated that the “meeting minutes from recent end-of-phase interactions with the [U.S. Food and Drug Administration (“FDA”)]” “reflected heightened FDA concerns regarding pociredir’s benefit-risk profile in SCD, stemming from an unexpectedly high rate of secondary hematologic malignancies observed with Tazverik® (tazemetostat), another PRC2 inhibitor, which was withdrawn from the global market in March 2026.” After submitting further information, the FDA “concluded that any pharmacological intervention targeting the PRC2 complex carries equivalent malignancy risk regardless of the specific subunit engaged.” As a result, the Company has “no viable regulatory path forward for further clinical development of pociredir.” Following this news, the price of Fulcrum Therapeutics stock declined from a closing price on June 1, 2026 of $6.42 per share to close at $3.14 per share on June 2, 2026, a decline of $3.28 per share, or by 51.09%. WHY CONTACT KAPLAN FOX Kaplan Fox is a leading national law firm focusing on complex litigation with offices in New York, Oakland, Los Angeles, Chicago and New Jersey. With over 50 years of experience in securities litigation, Kaplan Fox offers the professional experience and track record that clients demand. Through prosecuting cases on the federal and state levels, Kaplan Fox has successfully shaped the law through winning many important decisions on behalf of our clients. For more information about Kaplan Fox & Kilsheimer LLP, you may visit our website at www.kaplanfox.com. This press release may be considered Attorney Advertising in some jurisdictions under the applicable law and ethical rules. If you have any questions about this investigation, please contact: CONTACT:Jeffrey P. CampisiKAPLAN FOX & KILSHEIMER LLP800 Third Avenue, 38th FloorNew York, New York 10022(212) 329-8571jcampisi@kaplanfox.com Laurence D. KingKAPLAN FOX & KILSHEIMER LLP1999 Harrison Street, Suite 1501Oakland, California 94612(415) 772-4704lking@kaplanfox.com The submission of this form does not create an attorney-client relationship, nor an obligation on the part of Kaplan Fox to retain you as a client. Any information you submit will be maintained as confidential. If Kaplan Fox, in its sole discretion, believes that you might be an appropriate client, Kaplan Fox will contact you to discuss the matter and whether to establish an attorney client relationship. By signing this form you are authorizing us to contact you regarding this case and/or future cases. Connect with Kaplan Fox. Receive a complimentary case review now. Contact Us Fulcrum Therapeutics, Inc. Investigation: Learn More Now See the Case Lucid Group, Inc. Class Action Alert: Learn More Now See the Case AeroVironment, Inc. Class Action Alert: Learn More Now See the Case Zoetis, Inc. Class Action Alert: Learn More Now See the Case Veritone, Inc. Class Action Alert: Learn More Now See the Case FS KKR Capital Corp. Class Action Alert: Learn More Now See the Case Sportradar Group AG Shareholder Alert: Learn More Now See the Case Badger Meter, Inc. Shareholder Alert: Learn More Now See the Case Simply Good Foods Shareholder Alert: Learn More Now See the Case Regencell Bioscience Holdings. Shareholder Alert: Learn More Now See the Case GoDaddy, Inc. Shareholder Alert: Learn More Now See the Case ImmunityBio, Inc. Class Action Alert: Learn More Now See the Case